July 18, 2004

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Low Carb Fertility Problems?

New Scientist Magazine reports this month that a recent study indicates that high protein diets reduce fertility. They suggest that women trying to conceive not remain on the Atkins diet. Do you need to pay heed?

Hey, I am not a doctor, nor even a medical researcher, nor do I play one or the other on television. However, there are some things I think you need to keep in mind:

* First, and most important, the study in question, done at the Colorado Center for Reproductive Medicine, was not a human study, but rather was done on mice and cows. In these two species, a high protein diet reduced the chances of an embryo emplanting in the uterine wall. Neither mice nor cows are species with a hunter-gatherer history; I find it a stretch to assume that a high protein diet would have the same affect on humans as on these animals. Which leads us to the fact that...

* The problem which leads to reduced fertility in mice and cows on a high protein diet is an increase in metabolic ammonium in the reproductive tract. Jeff Volek from the University of Connecticut at Storrs reports that ammonium levels do not increase in humans on the Atkins diet, which raises the question of whether ammonium levels increase in the reproductive tract. There is no evidence that it does.

* Studies of paleoanthropological evidence combined with studies of the few remaining hunter-gatherer tribes indicate that the hereditary diet of human kind for the most part consists of about 50% animal products, plus vegetables, fruit in season, nuts and seeds, and other plant matter - but not grains or beans (and of course, not sugar!) This would, of course, be a high protein diet. It seems unlikely that a diet that impaired human fertility would have lead to our being the most successful species on the planet.

* A very common cause of infertility is polycystic ovarian syndrome. How common? An estimated 70% of infertility problems stemming from ovulation difficulties come from PCOS. It is accepted that PCOS stems from hyperinsulinemia - carbohydrate intolerance - and a low carbohydrate diet is the first line of treatment. Indeed, I have heard from women with PCOS for whom a low carbohydrate diet was sufficient treatment to allow them to get pregnant.

* It's also important to remember that insulin-based illnesses are common during pregnancy. Gestational diabetes affects between 3-6% of pregnant women. Preeclampsia is also related to insulin levels, and is more common in obese women with insulin resistance. I find it doubtful that a diet high in carbohydrates during pregnancy is a good idea for anyone with a weight problem or insulin resistance.

In short, I am unconvinced that this is a big problem, but it's worth keeping an eye on.

If you are trying to get pregnant, and your doctor has determined that you have a problem with a fertilized egg implanting, or you're simply concerned, remember this: A low carbohydrate diet is not necessarily synonymous with a high protein diet. There is no reason why you can't eat 65 grams or so of protein a day - about 10-12 ounces of meat, eggs, or cheese - and make up the rest of your diet with low carb vegetables and healthy fats. Eat less meat and more avocados, healthy oils, olives, and nuts and seeds, to make up the rest of your calories. You could also look at some of the diets based on the glycemic index; I include one in How I Gave Up My Low Fat Diet and Lost 40 Pounds, but there are plenty of g-index diets out there.

I just hope that the coverage of this story doesn't convince women that they'd do better to eat cold cereal, white bread, and pasta when trying to conceive than they would to eat meat, poultry, eggs, fish, and plenty of salads. That would be a dreadful mistake.

Posted by HoldTheToast at July 18, 2004 03:02 PM